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Molecules and Water in the Living Cell

An Introduction to the Concept of “Transient Linear Hydration”

 An Educational Book by J.C. Collins, PhD
 

The Concept is used to explain how Water may have directed the
Evolution of Vital Molecules and how it coordinates
their Motions and Interactions to give Cells Life.

"Water is the essence of life"
 

Living cells function with such high efficiency and order that the aqueous environment within them must possess some unique spatial properties to coordinate motions and interactions between all the ionic and molecular parts.

Based on current concepts, motion and order within molecules in living cells are controlled by transitions between specific thermodynamic states. However, water within cells is dynamic - it does not undergo specific transitions and its molecules do not bind tightly together. Instead, it appears that environmental order is provided by the transient, dipolar-alignment of water molecules between ions and charge-centers on molecules to permit proton pulses to oscillate back and forth to delocalize charge. Although the alignments have preferred lengths for maximum charge stabilization, the water molecules composing them are still dynamic - only the short, linear units that propagate the proton charge are ordered. By repeatedly defining preferred distances between oppositely-charged centers as multiples of hydrogen-bonded water molecules to minimize energy potential, motions and interactions are quantized. Thus, based on the TLH hypothesis, the high efficiency and order evident within living cells is provided by the dynamic, repetitive, linear quantization of aqueous space by the transient alignment of water molecules between the ionic and molecular parts.

This presentation provides a brief introduction to the spatial properties of water, its intimate involvement with the major classes of molecules in the living cell and how it appears to have selected critical molecules, as they first formed, to satisfy its own hydrogen-bonding, spatial properties. Pages 19 and 20 provide a more detailed description of the linearizing property of water and, page 47, an explanation of how protons appear to perform the extremely rapid, almost superconductive, transmission of positive pulses through the axonal regions of nerve cells based on the stabilization of linearized water by the lipid wall.

The entire book, or it’s parts may be read on the Web or downloaded as a PDF file - free of charge.